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KMID : 0061119840120000064
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Bulletin of the Clinical Research Institute
1984 Volume.12 No. 0 p.64 ~ p.64
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Circadian Rhythm of Serum Cortisol in Child
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Suh, Byng_kyu
Lee, Byung-Churl/Lee, Du-Bong
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Abstract
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It is well known that serum cortisol levels show atypical circadian rhythm in 24 hours duration in normal adult. However, the time of emergence of the cortisol circadian rhythm in man; has not been clarified postnatally,- Thus in the present study, the age at which infants and children display a pattern of circadian rhythm of cortisol comparable to that of normal adult was investigated.
The radioimmunoassaY method was used to study the development of serm cortisol circadian rhythm in a total of 50 children. Patients with endocrine diseases, congenital anomalies and diseases of the central nervous system were excluded from this study.
A distinct circadian rhythm with an amplitude comparable to that, of an adult emerged of approximately 1 year after birth.
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